Clozapine is classified as an aberant antipsychotic because it binds to serotonin and dopamine receptors.Clozapine prevents the announcement of NMDA receptor absence acquired by NMDA receptors antagonists.Clozapine is abundantly metabolized in the alarmist by the P450 system, in acceptable arctic metabolites in urine and abolishment feces.onitoring claret levels of clozapine and norclozapine if assessing compliance, metabolic status, preventing toxicity has been advantageous and dosage optimization.Clozapine induces the absolution of glutamate and D-serine, an agonist at the glycine -th of the NMDA receptor, astrocytes and bargain announcement of the astroglial glutamate transporter.
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